Tupi derived from the word "Tufi" which was a vine chewed by native Bla'an tribes who first inhabited the land. Tufi was abundant in the original forests and had a refreshing taste.

As it lies in the dormant foot of Mt. Matutum, Tupi's fertile soil of volcanic ash offers a great enticement to speculators and investors particularly in the field of agriculture.

In 1936 during the commonwealth government, President Manuel L. Quezon appointed Major General Paulino Santos as General Manager for the development of Koronadal and the vast land in the Allah Valley. Settlers from Luzon and Visayas starting to arrive transforming the once large forest into a flourishing area of agriculture.

The Bario of Tupi was created into a municipality of Tupi by virtue of executive order 612 of President Elpidio Quirino on September 11, 1953. The first set of appointed officials were inducted on October 2 of that year.

Tupi's climate and soil type makes it suitable to all types of crop and livestock production. Tupi aside from pineapple, tropical fruits and vegetables is identified as suited for high-value commercial crops (HVCC) like asparagus and papaya. Cutflower production is one crop that is putting Tupi on the regional map. Tupi is likewise identified as one of the areas in the province well suited for poultry production. To date, there are around 34 major poultry raisers scattered in the municipality with minimum of 10,000 heads capacity. Tupi had been identified in the SOCCSKSARGEN Growth Plan as one of the areas where a satellite Food Terminal shall be located. To date, a private organization, the DARBCI initiated the establishment of an initial 70 hectare Economic Zone within the Municipality of Tupi. One of the future investment eyed as an economic booster is the establishment of an Integrated Food Terminal. On this aspect, private investors are welcome to finance major economic endeavors within the economic zone.

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Wikipedia