Truth serum

"Truth serum" is a colloquial name for any of a range of psychoactive drugs used in an effort to obtain information from subjects who are unable or unwilling to provide it otherwise. These include ethanol, scopolamine, 3-quinuclidinyl benzilate, midazolam, flunitrazepam, sodium thiopental and amobarbital, among others.

Although a variety of such substances have been tested, serious issues have been raised about their use scientifically, ethically and legally. There is currently no drug proven to cause consistent or predictable enhancement of truth-telling. Subjects questioned under the influence of such substances have been found to be suggestible and their memories subject to reconstruction and fabrication. When such drugs have been used in the course of investigating civil and criminal cases, they have not been accepted by Western legal systems and legal experts as genuine investigative tools. It has been suggested that their use is a potential violation of the Fifth Amendment of the U.S. Constitution (the right to remain silent). Concerns have also been raised internationally through the European Court of Human Rights arguing that use of a truth serum could be considered a violation of a human right to be free from degrading treatment, or could be considered a form of torture. It has been noted to be a violation of the Inter-American Convention to Prevent and Punish Torture.

"Truth serum" has also been used in the evaluation of psychotic patients in the practice of psychiatry. In a therapeutic context, the controlled administration of intravenous hypnotic medications is called "narcosynthesis" or "narcoanalysis". Such application was first documented by Dr. William Bleckwenn in 1930. It is argued that it may be used to procure vital diagnostic or therapeutic information. Reliability and suggestibility of patients are still concerns. It may also provide patients with a functional respite from catatonia or mania.

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