Tropic hormones are hormones that have other endocrine glands as their target. Most tropic hormones are produced and secreted by the anterior pituitary. The hypothalamus secretes tropic hormones that target the anterior pituitary, and the thyroid gland secretes thyroxine, which targets the hypothalamus and therefore can be considered a tropic hormone.
The term is from Ancient Greek (tropikós), in the sense "of or pertaining to a turn or change", meaning "causing a change, affecting"; this is the same origin as and . This should not be confused with , as in similar-sounding trophic hormone – the words and concepts are both unrelated. Tropic hormones are contrasted with non-tropic hormones, which directly stimulate target cells.
Tropic hormones from the anterior pituitary include:
In turn, the hypothalamus controls the release of hormones from the anterior pituitary by secreting a class of hypothalamic neurohormones called releasing and release-inhibiting hormones—which are released to the hypothalamo-hypophyseal portal system and act on the anterior pituitary.
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