Titiopolis (Greek: Τιτιούπολις) was a town in the Roman province of Isauria.
Some refer to the town by the name Titopolis, but a coin minted there in the time of Emperor Hadrian bears on the reverse the word ΤΙΤΙΟΠΟΛΙΤΩΝ (Of the inhabitants of Titiopolis). Other sources cited in the presentation about that coin to the Royal Numismatic Society give the same form. These concern the names of bishops of Titiopolis (considered below) and also the information given by the Hieroclis Synecdemus, by George of Cyprus, and by Constantine Porphyrogenitus, according to which Titiopolis was one of the cities of the Isaurian Decapolis.
The ruins of Titiopolis lie about 4 kilometres north-north-west of Anamur.
Titiopolis was also the seat of an ancient Bishopric.
Le Quien mentions three bishops of Titiopolis:
The see of Titiopolis is mentioned in the 6th century Notitia episcopatuum of Antioch and, after Isauria was annexed to the Patriarchate of Constantinople in about 732, in the Notitia episcopatuum of that church and in that of Leo the Wise in about 900 and that of Constantine Porphyrogenitus in about 940.
The last mention of Titiopolis as a residential see is by William of Tyre in the late 12th century. He speaks of it as one of the 24 suffragan sees of Seleucia in Isauria.