Tinsley Randolph Harrison

Tinsley Randolph Harrison (March 18, 1900 – August 4, 1978) was an American physician and editor of the first five editions of Harrison's Principles of Internal Medicine. Harrison specialized in cardiology and the pathophysiology of heart disease.

Harrison was born in Talladega, Alabama, on March 18, 1900. He was the son of Groce Harrison, himself a sixth-generation physician. Having graduated from high school at the age of 15, Harrison attended the University of Michigan, where he also completed one year of medical school before transferring to Johns Hopkins School of Medicine in the fall of 1919. His roommate and tennis partner at Johns Hopkins was Alfred Blalock, with whom he developed a close lifelong friendship. He completed his internship at Peter Bent Brigham Hospital in Boston, returned to Hopkins for further training in internal medicine, and completed his residency at Vanderbilt University where he served as the first Chief Resident in the Department of Medicine.

Harrison's special field of interest was cardiovascular medicine as well as the pathophysiological mechanisms of disease. His name is best known among physicians as the founding editor and editor-in-chief of the first five editions of Harrison's Principles of Internal Medicine. The text initiated several unique approaches to medical textbook writing, and remains, in its current edition, one of the most widely read and regarded textbooks in medicine.

Harrison's career included extensive work in research, publishing, medical education, and medical practice. He taught at Vanderbilt University's school of medicine, at what was then the Bowman Gray School of Medicine at Wake Forest University in North Carolina and at what is today the University of Texas Southwestern Medical School in Dallas, Texas.

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