The Vespasian Psalter (London, British Library, Cotton Vespasian A I) is an Anglo-Saxon illuminated psalter decorated in a partly Insular style produced in the second or third quarter of the 8th century. It contains an interlinear gloss in Old English which is the oldest extant English translation of any portion of the Bible. It was produced in southern England, perhaps in St. Augustine's Abbey or Christ Church, Canterbury or Minster-in-Thanet, and is the earliest illuminated manuscript produced in "Southumbria" to survive.
The Psalter belongs to a group of manuscripts from Southern England known as the Tiberius group, also including the , Barberini Gospels, the Book of Cerne, the Tiberius Bede, and the Book of Nunnaminster.
The psalter contains the Book of Psalms together with letters of St. Jerome, hymns and canticles. The main scribe was also the artist of the miniatures. It was written in Latin on vellum, using a southern English Uncial script with Rustic Capital rubrics. There were additions made by a scribe named Eadui Basan in an English Carolingian minuscule. The English gloss was written in a Southumbrian pointed minuscule.