Thomas Walpole (6 October 1727 – March 1803), styled from 1756 The Hon. Thomas Walpole, was a British MP and banker in Paris.
Thomas Walpole was born into a political family. The second son of the 1st Baron Walpole and his wife Mary, nee Lombard, he was the nephew of Sir Robert Walpole, the prime minister from 1721 to 1742.
Walpole entered into partnership with the merchant Sir Joshua Vanneck, and married his daughter Elizabeth Vanneck on 14 November 1753. She died on 9 June 1760.
He was MP for Sudbury from 1754 to 1761, and MP for Ashburton from 1761 ot 1768. In 1762 he was involved in efforts to engineer William Pitt the Elder into a rapprochement with the Duke of Newcastle. In 1768 he succeeded his cousin Horace Walpole as MP for Lynn. In the early 1770s Walpole led a group of investors, including Benjamin Franklin, to seek from the crown a land grant in Ohio. He remained MP for Lynn until 1784, when he was succeeded by his nephew Horatio Walpole.
In 1787 he married his second wife, Jeanne-Marguerite Batailhe de Montval. From 1799 until his death Walpole lived in a large house, today named Walpole House, on Chiswick Mall, Chiswick.
His son Thomas (1755–1840) was British Ambassador to Munich.