Thomas Ostrom Enders (November 28, 1931 – March 17, 1996) was a United States diplomat.
Thomas O. Enders was born on November 28, 1931 in Hartford, Connecticut. He was educated at Yale University, where he was a member of the Scroll and Key society, receiving a B.A. in 1953; at the University of Paris, receiving a M.A. in 1955; and Harvard University, receiving a M.A. in 1957.
In 1958, Enders joined the United States Foreign Service as an intelligence research specialist. From 1960 to 1963, he was a visa officer and then an economic officer in . From 1963, he was supervisory international economist at the Bureau of European Affairs. In 1966, he was a special assistant in the Office of the Under Secretary of State for Political Affairs. In 1968, he became Deputy Assistant Secretary of State for International Monetary Affairs.
From 1969, he was deputy chief of mission in Belgrade. From 1971 to 1973, he held the same position in Phnom Penh. In 1974, Enders became Assistant Under Secretary of State for Economic and Business Affairs.
In 1976, US President Gerald Ford nominated Enders as United States Ambassador to Canada; Enders held this post from February 17, 1976 to December 14, 1979. From 1979, he was United States Ambassador to the European Communities.