Thomas Cartwright (c. 1635 – 27 December 1703) was a 17th-century English architect.
Cartwright was born in Hertfordshire; his parents were Timothy Cartwright of Gloucestershire and Penelope Segar, whose first husband was Nicholas Charles.
Cartwright became a Liveryman of the Masons' Company, and was worked in London on numerous buildings in the aftermath of the Great Fire of London of 1666. He was contractor for St Antholin, St Benet Fink, and St Mary le Bow, three of the Wren churches. He worked as an architect on the Royal Exchange, with sole charge after Edward Jerman died in 1668. He was the architect employed by Sir Robert Clayton, president of the St Thomas' Hospital, to rebuild and the hospital and nearby St Thomas Church on St Thomas Street, SE1, on what is now the site of London Bridge Station. He also designed Portland College for the Disabled in Sherwood Forest near Mansfield, Nottinghamshire