Thogotovirus
| Orthomyxoviridae | |
|---|---|
.jpg) |
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| Electron micrograph of Bourbon virus (scale bar: 100 nm) |
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| Virus classification | |
| Group: | Group V ((−)ssRNA) |
| Order: | Unassigned |
| Family: | Orthomyxoviridae |
| Genus: | Thogotovirus |
| Type species | |
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Thogoto virus |
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| Species | |
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Araguari virus |
|
Araguari virus
Aransas Bay virus
Batken virus
Bourbon virus
Dhori virus
Jos virus
Sinu virus
Upolu virus
Thogotovirus is a genus of enveloped RNA viruses, one of seven genera in the virus family Orthomyxoviridae. Their single-stranded, negative-sense RNA genome has six or seven segments. Thogotoviruses are distinguished from most other orthomyxoviruses by being arboviruses – viruses that are transmitted by arthropods, in this case usually ticks. Thogotoviruses can replicate in both tick cells and vertebrate cells; one subtype has also been isolated from mosquitoes. A consequence of being transmitted by blood-sucking vectors is that the virus must spread systemically in the vertebrate host – unlike influenza viruses, which are transmitted by respiratory droplets and are usually confined to the respiratory system.
Thogoto virus (THOV) is the type species; the genus also contains the species Dhori virus (DHOV) and its subtype Batken virus, as well as the species or strains Araguari virus, Aransas Bay virus (ABV), Bourbon virus, Jos virus (JOSV) and Upolu virus (UPOV), which have yet to be confirmed by the International Committee on Taxonomy of Viruses (ICTV). A wide range of mammals are infected by members of the genus; some types also infect birds. THOV causes disease in livestock. THOV, DHOV and Bourbon virus can infect humans, and have occasionally been associated with human disease.
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