Theophilus Leigh D.D. (died 3 January 1785) was an English academic administrator at the University of Oxford.
Leigh was elected Master (head) of Balliol College, Oxford on 12 May 1726, through the influence of James Brydges, 8th Baron Chandos, his uncle. He held the post until his death in 1785, the longest incumbent in that role. Leigh was from outside the College, and a great-uncle of Jane Austen. He was Vice-Chancellor of Oxford University from 1738 until 1741.