In the fictional universe of Warhammer 40,000, the Primarchs were engineered superhumans created by the Emperor to command his future Legions of Space Marines. Originally twenty in number, they were said to have been created using the Emperor's own DNA. Of the 20 Primarchs, 18 are known while two remain mysterious. Their genetic material was also used to form the basis of the Legions they would command.
All were created in genetic laboratories hidden on Terra, and were almost completely matured before their incubation pods were scattered across the galaxy. The cause of this is unknown; the forces of Chaos, the Emperor and the Primarchs themselves are claimed in varying tales to be responsible for snatching the infant Primarchs' incubation cradles from Earth and dispersing them through the Warp.
According to the novel False Gods, The Emperor might have allowed the forces of Chaos to scatter the Primarchs across the Galaxy for purposes unknown. Also, according to Chaos, the Emperor might have procured the power needed to create the Primarchs from the Chaos gods via unknown means. As the Great Crusade progressed, the Emperor was reunited with each of them as his armies re-established contact with the worlds on which the Primarchs had come to rest. Most had, in the intervening time, risen to positions of power or infamy as a result of their remarkable physiology and abilities. At least two had been subject to noticeable mutation; Sanguinius, who had angelic wings and was reported to be psychic; and Magnus, who had bright red skin and was widely known to have formidable psychic talent.
The Primarchs were the twenty genetically-engineered "sons" of the Emperor. The Emperor used his own DNA in their creation, and they were designed to be far superior to the average human: immensely larger, stronger, hardier, faster, and more intelligent. They were also incredibly charismatic, as their main role was to be generals and leaders of the Imperial military. In addition, their genetic material was used to create their own "sons," the Adeptus Astartes. But while the Space Marines are known to be better in every aspect compared to baseline humans, they are but pale shadows compared to their gene-sires who are akin to demigods.