The Garstang and Knot-End Railway [sic] was a railway line, between Garstang and Knott End-on-Sea, devised to provide an outlet for farmers in the Over Wyre area of the Fylde in Lancashire, England, to transport their produce elsewhere in the country.
In December 1863, a prospectus was produced naming six directors of the Garstang and Knot-End Railway. These were: John Russell, Julian Augustus Tarner, Henry Gardner, Colonel James Bourne, Richard Bennett and James Overend. They were given a capital of £60,000 to build an 11 1⁄2-mile-long (18.5 km) railway to Knott End from a junction with the Lancaster and Preston Junction Railway. The railway was authorised by Act of Parliament on 30 June 1864.
The Garstang and Knot-End Railway Company took 5½ years to build a seven-mile (11 km) single-track line from Garstang only as far as Pilling, across once desolate peat bogland that was being reclaimed for farming. The final cost was £150,000. The line opened to services on 5 December 1870, running with a single locomotive, Hebe, although the official opening ceremony was not until 14 December 1870. Trains were mixed (passengers and goods), and goods wagons were uncoupled along the line to be collected on the return journey. Passengers could board at any point along the line by request.