The Best of The Byrds: Greatest Hits, Volume II is the third greatest hits album by the American rock band The Byrds, but only the second to be released in the United States, since the earlier The Byrds' Greatest Hits Volume II had only been issued in the UK. The album was released in the U.S. by Columbia Records on November 10, 1972 (see 1972 in music) in lieu of any new Byrds' product during that year. It spent a total of thirteen weeks on the Billboard Top LPs & Tapes chart and peaked at number 114.

Released just prior to the highly publicized reunion of the five original members of The Byrds, the album was compiled with input from the band's guitarist and leader Roger McGuinn, but offered a somewhat erratic survey of the band's later years. The bulk of the album's songs are drawn from the years 1969 through to 1971, with the 1968 albums The Notorious Byrd Brothers and Sweetheart of the Rodeo only being represented by "Wasn't Born to Follow" and "You Ain't Goin' Nowhere" respectively. The album also included "He Was a Friend of Mine", which had originally appeared on 1965's Turn! Turn! Turn! album, a period already covered by the band's first compilation album, The Byrds' Greatest Hits.The Best of The Byrds: Greatest Hits, Volume II featured a number of the band's U.S. charting singles, including "Ballad of Easy Rider" (#65), "Jesus Is Just Alright" (#97), "Chestnut Mare" (#121), and "You Ain't Goin' Nowhere" (#74). However, since none of these singles reached the U.S. Top 40, they couldn't really be considered bona fide hits.

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