Texas State Highway 351
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| Route information | ||||
| Maintained by TxDOT | ||||
| Length: | 25.122 mi (40.430 km) | |||
| Existed: | 1943 – present | |||
| Major junctions | ||||
| West end: |
  Bus. US 83 in Abilene
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 I-20 in Abilene |
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| East end: |
  US 180 / SH 6
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State Highway 351 (SH 351) is a 25.122-mile-long (40.430 km) Texas state highway that travels from Abilene northeast to an intersection with U.S. Route 180 (US 180) west of Albany. The highway was designated in 1943 as a replacement for US 80 Alternate.
SH 351 begins at an intersection with US 83 Business (Treadaway Boulevard) in Abilene. The highway heads east through Abilene along Ambler Avenue. It curves to the northeast prior to a diamond interchange with Interstate 20 (I-20). The highway heads northeast as it leaves the Abilene city limits on its way to intersections with FM 1082, FM 604, and FM 3522. It continues to the northeast to its eastern terminus at a concurrency of US 180 and SH 6.
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