Terre Bleue Creek is a stream in St. Francois and Ste. Genevieve counties of eastern Missouri. It is a tributary of the Big River.
The source is located at: 37°52′32″N 90°19′12″W / 37.87556°N 90.32000°W and the confluence is at: 37°56′29″N 90°30′59″W / 37.94139°N 90.51639°W.
Terre Bleue Creek was so named on account of the color of the dirt on its course, terre bleue being a name meaning "blue earth" in French.