Technetium exametazime

Technetium (^99mTc) exametazime

Clinical data
Trade names	Ceretec
License data	US FDA: Ceretec
Pregnancy category	US: C (Risk not ruled out)
Routes of administration	Intravenous
ATC code	V09AA01 (WHO) V09HA02 (WHO) (labelled leucocytes)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name [[(3RS,3'RS)-3,3'-[(2,2-Dimethyltrimethylene)diimino][di-2-butanone]dioximato](3-)-N,N',N'',N''']oxotechnetium (99mTc)
CAS Number	99944-78-2 N
PubChem CID	9552069
UNII	3B744AG22N
Chemical and physical data
Formula	C13H25N4O3Tc
Molar mass	384.3655 g/mol
NY (what is this?)

Technetium (^99mTc) exametazime is a radiopharmaceutical sold under the trade name Ceretec, and is used by nuclear medicine physicians for the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime (the part without technetium) is sometimes referred to by its chemical name of hexamethylpropyleneamine oxime or HMPAO.

The drug consists of two of the three stereoisomers of hexametazime (HMPAO), one of which is shown here, the other being its enantiomer. The third stereoisomer is the meso form. Exametazime acts as a chelating agent for the radioisotope technetium-99m.

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Wikipedia