"Take Care" is the title track from Canadian rapper Drake's 2011 album of the same name. The song features guest vocals from Barbadian singer Rihanna. The song samples Jamie xx's remix of Gil Scott-Heron's version of "I'll Take Care of You". "Take Care" was released as the fifth single from the album on February 21, 2012. It is a club song about a couple in a relationship acknowledging they have been hurt in their past, but will look after one another.

"Take Care" peaked at number seven on the US Billboard Hot 100, while also reaching the top ten in Australia, Denmark, New Zealand, and the United Kingdom. It further peaked at numbers two and eight on the US Rap Songs and Pop Songs charts, and charted within the top ten of the UK Singles Chart. The song's accompanying music video, directed by Yoann Lemoine, depicts simplistic art including Drake and Rihanna's characters in an intimate relationship, with other scenes featuring animals such as a bull, black-throated magpie-jay and tropical fish, and various outdoor landscapes. The video portrays the ups and downs of a relationship with poaching and wildfires. Critics praised the video for its simple and minimalistic theme.

"Take Care" was written by Drake (credited as Aubrey Graham), Noah Shebib, Anthony Palman and James Smith, better known as Jamie xx. Production of the song was handled by Jamie xx and Shebib under his production name Noah "40" Shebib. It was recorded by Shebib and Ruben Riveara at Metalworks Studios, Ontario, Canada. The engineer was Noel Cadastre, and was assisted by Greg Morrison. It was mixed by Noel "Cadget" Campbell at Studio 206, Ontario, Canada. All instrumentation was provided for by Jamie xx, with exception of the guitar, which was provided for by Romy Madley Croft - Jamie xx's fellow band member from The xx; drum programming was completed by Shebib.Background vocals were performed by Gil Scott-Heron. "Take Care" contains a sample of Brook Benton's song "I'll Take Care of You". Permission and license was granted by XL Recordings. Rihanna appears on the track as a featured artist courtesy of The Island Def Jam Music Group.

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