Takatsukasa Hisasuke (鷹司 尚輔?, 1726 – April 19, 1733), son of Konoe Iehiro and adopted son of Fusahiro, was a kuge or Japanese court noble of the Edo period (1603–1868). He died at age 8 of illness after inheriting the Takatsukasa family at age 5. His wife and he did not have a son, but they adopted one Mototeru.