System LK

Sequent calculus is, in essence, a style of formal logical argumentation where every line of a proof is a conditional tautology (called a sequent by Gerhard Gentzen) instead of an unconditional tautology. Each conditional tautology is inferred from other conditional tautologies on earlier lines in a formal argument according to rules and procedures of inference, giving a better approximation to the style of natural deduction used by mathematicians than David Hilbert's earlier style of formal logic where every line was an unconditional tautology. There may be more subtle distinctions to be made; for example, there may be non-logical axioms upon which all propositions are implicitly dependent. Then sequents signify conditional theorems in a first-order language rather than conditional tautologies.

Sequent calculus is one of several extant styles of proof calculus for expressing line-by-line logical arguments.

In other words, natural deduction and sequent calculus systems are particular distinct kinds of Gentzen-style systems. Hilbert-style systems typically have a very small number of inference rules, relying more on sets of axioms. Gentzen-style systems typically have very few axioms, if any, relying more on sets of rules.

Gentzen-style systems have significant practical and theoretical advantages compared to Hilbert-style systems. For example, both natural deduction and sequent calculus systems facilitate the elimination and introduction of universal and existential quantifiers so that unquantified logical expressions can be manipulated according to the much simpler rules of propositional calculus. In a typical argument, quantifiers are eliminated, then propositional calculus is applied to unquantified expressions (which typically contain free variables), and then the quantifiers are reintroduced. This very much parallels the way in which mathematical proofs are carried out in practice by mathematicians. Predicate calculus proofs are generally much easier to discover with this approach, and are often shorter. Natural deduction systems are more suited to practical theorem-proving. Sequent calculus systems are more suited to theoretical analysis.

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Wikipedia