Suprax

Cefixime
Clinical data

Trade names	many
AHFS/Drugs.com	Monograph
MedlinePlus	a690007
Pregnancy category	B
Routes of administration	by mouth (capsule or suspension)
ATC code	J01DD08 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	40% to 50%
Protein binding	Approximately 60%
Biological half-life	Variable Average 3 to 4 hours
Excretion	Kidney and biliary
Identifiers
IUPAC name (6R,7R)-7-{[2-(2-Amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino}-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	79350-37-1^Y
PubChem CID	5362065
DrugBank	DB00671^Y
ChemSpider	4514923^Y
UNII	XZ7BG04GJX
KEGG	D00258^Y
ChEBI	CHEBI:472657^Y
ChEMBL	CHEMBL1541^Y
ECHA InfoCard	100.119.331
Chemical and physical data
Formula	C₁₆H₁₅N₅O₇S₂
Molar mass	453.452 g/mol
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(/C=C)CS[C@@H]1[C@@H]2NC(=O)C(=N\OCC(=O)O)/c3nc(sc3)N)C(=O)O
InChI InChI=1S/C16H15N5O7S2/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27)/b20-9-/t10-,14-/m1/s1^Y Key:OKBVVJOGVLARMR-QSWIMTSFSA-N^Y
^NY (what is this?)

Cefixime is an antibiotic useful to treat a number of bacterial infections. This includes otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. For gonorrhea typically only one dose is required. In the United States it is a second line treatment to ceftriaxone for gonorrhea. It is taken by mouth.

Common side effects include diarrhea, abdominal pain, and nausea. Serious side effects may include allergic reactions and Clostridium difficile diarrhea. It is not recommended in people with a history of a severe penicillin allergy. It appears to be relatively safe during pregnancy. It is in the third generation cephalosporin class of medications. It works by disrupting the bacteria's cell wall resulting in its death.

Cefixime was approved for medical use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is not available as a generic medication in the United States. The wholesale cost in the developing world is about 0.26 to 2.09 USD per dose. In the United States a course of treatment costs about 100 to 200 USD as of 2015.

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Wikipedia