"Straight Tequila Night" is a song written by Debbie Hupp and Kent Robbins, and recorded by American country music singer John Anderson. It was released in December 1991 as the second single from Anderson's album Seminole Wind. It reached number-one on the country charts in the United States and Canada. It was Anderson's first number one song since 1983 and considered his comeback single.

The song is a mid-tempo number in which the narrator is a person counseling a man in a tavern, who is regarding a frequent female patron. The narrator advises the man not to speak with her when she is consuming straight tequila because it will make her think of her former significant other with whom she had recently ended a relationship, adding that she is otherwise friendly especially when consuming any other alcoholic beverage.

A music video was filmed for the song, and was directed by Steve Boyle. It has aired on CMT, TNN and Great American Country; and has also been seen on CMT Pure Country.

In 2014, country artist Kevin Moon released the song as a duet with John Anderson as the first single on his CD, "Throwback."

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