Store Kannikestræde is a street in the Old Town of Copenhagen, Denmark, connecting Frue Plads to Købmagergade. Its history is closely associated with the University of Copenhagen and some of Copenhagen's oldest halls of residence are located in the street. It has been pedestrianized since 1973.
Lille Kannikestræde is a short side street which extends from the south side of Store Kannikestræde, connecting it to Skindergade.
Kannik is derived from canonicus. The street takes its name after the eight canons associated with Church of Our Lady.
After the Reformation, University of Copenhagen took over the Roskilde bishops' premises north of the church (now known as the University Quadrangle). The houses in Store Kannikestræde were used as residences for professors at the University. Ole Worm who lived with his family on the corner of Store Kannikestræde and Fiolstræde established a museum of curiosities in his home.
In the early 18th century the University had a total of 11 residences for professors in the street. They were all destroyed along with the other houses in the street in the Copenhagen Fire of 1728. Five of them were rebuilt in 1735 while the other six were not rebuilt until the 1750s. The houses were all designed by Joachim Frederik Ramus, professor in mathematics. They were of considerable size and each contained a single residence, demonstrating the high social status of the professors at the time.
The street was pedestrianized on 23 May 1973 along with Købmagergade and Rosengården.
Three of the oldest halls of residence in Copenhagen are located in the street. Regensen was founded by Christian IV, although only the two lower floors of the section to the east of the gate in Store Kannikestræde date from the original building of 1623. The section west of the gate was destroyed in the fire of 1728 but rebuilt in 1749. The third floor was added in 1777.