A stinging plant or a plant with stinging hairs is a plant with hairs (trichomes) on its leaves or stems that are capable of injecting substances that cause pain or irritation.
Other plants, such as opuntias, have hairs or spines that cause mechanical irritation, but do not inject chemicals. Stinging hairs occur particularly in the families Urticaceae, Loasaceae, Boraginaceae (subfamily Hydrophylloideae) and Euphorbiaceae. Such hairs have been shown to deter grazing mammals, but are no more effective against insect attack than non-stinging hairs. Many plants with stinging hairs have the word "nettle" in their English name, but may not be related to "true nettles" (the genus Urtica).
Though several unrelated families of plants have stinging hairs, their structure is generally similar. A solid base supports a single elongated cell with a brittle tip. When the tip is broken, the exposed sharp point penetrates the skin and pressure injects toxins. The precise chemicals involved in causing pain and irritation are not yet fully understood.
Stiff hairs or trichomes without the ability to inject irritating compounds occur on the leaves and stems of many plants. They appear to deter feeding insects to some degree by impeding movement and restricting access to the surface of the stem or leaf. Some plants have glandular hairs, either as well as non-glandular hairs or instead of them. Glandular hairs have regions of tissue that produce secretions of secondary metabolites. These chemical substances can repel or poison feeding insects.
Stinging hairs may be defined as those with ability to inject a chemical substance through the skin of an animal causing irritation or pain. Since some glandular hairs can cause irritation merely by contact, the difference between "stinging hairs" and "irritating hairs" is not always clear. For example, the hairs of Macuna species are described in both ways. Some species of Macuna have sharply tipped hairs, in which the upper part easily breaks off, whereas other species have hairs that are blunter. In those subspecies of Urtica dioica that have stinging hairs (stinging nettles), these also have a point that easily breaks off, allowing the irritants in the cell below to enter through the skin. Being stung in this way has been shown to deter grazing mammals, such as rabbits, and even large herbivores such as cows. Many plant species respond to physical damage by producing a higher density of trichomes of all kinds.