State Road 45 (Florida)
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| Maintained by FDOT | ||||
| Length: | 300.547 mi (483.684 km) | |||
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| South end: |
 US 41 in Naples
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| North end: |
 US 41 / US 441 in High Springs
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| Location: | Venice, Florida |
| Length: | 2.968 mi (4.777 km) |
A major north–south highway extending almost the entire length of the Florida peninsula, State Road 45 (SR 45) is the unsigned Florida Department of Transportation designation of most of the current U.S. Route 41 in Florida. The southern terminus of SR 45 is an intersection with SR 90 in downtown Naples; the northern terminus is an intersection with US 441 (SR 25) in High Springs. South of Causeway Boulevard (SR 676) near Tampa, SR 45 is also known as the Tamiami Trail.
South and east of Naples, US 41 turns eastward as SR 90 as the Tamiami Trail crosses the Everglades on its way to Miami; north of High Springs, US 41 overlaps US 441 (SR 25) until their split in Lake City (from there US 41 continues to the Georgia border with the hidden SR 25 designation).
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