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Staphylococcus saprophyticus

Staphylococcus saprophyticus
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Staphylococcaceae
Genus: Staphylococcus
Species: S. saprophyticus
Binomial name
Staphylococcus saprophyticus
(Fairbrother 1940)
Shaw et al. 1951

Staphylococcus saprophyticus is a Gram-positive coccus belonging to the coagulase-negative Staphylococcus genus.S. saprophyticus is a common cause of community-acquired urinary tract infections.

S. saprophyticus was not recognized as a cause of urinary tract infections until the early 1970s, more than 10 years after its original demonstration in urine specimens. Prior to this, the presence of coagulase-negative staphylococci (CoNS) in urine specimens was dismissed as contamination.

In humans, S. saprophyticus is found in the normal flora of the female genital tract and perineum. It has been isolated from other sources, too, including meat and cheese products, vegetables, the environment, and human and animal gastrointestinal tracts.S. saprophyticus causes 10–20% of urinary tract infections (UTIs). In females 17–27 years old, it is the second-most common cause of community-acquired UTIs, after Escherichia coli. Sexual activity increases the risk of S. saprophyticus UTIs because bacteria are displaced from the normal flora of the vagina and perineum into the urethra. Most cases occur within 24 hours of sex, earning this infection the nickname "honeymoon cystitis".S. saprophyticus has the capacity to selectively adhere to human urothelium. The adhesin for S. saprophyticus is a lactosamine structure. S. saprophyticus produces no exotoxins.

Patients with urinary tract infections caused by S. saprophyticus usually present with symptomatic cystitis. Symptoms include a burning sensation when passing urine, the urge to urinate more often than usual, a 'dripping effect' after urination, weak bladder, a bloated feeling with sharp razor pains in the lower abdomen around the bladder and ovary areas, and razor-like pains during sexual intercourse. Signs and symptoms of renal involvement are also often registered.


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