The Henderson RoadRunners were an independent professional baseball team based out of Henderson, Nevada. They are members of the Western Division in the North American League and were scheduled to begin play in 2011 at Lied Field at Morse Stadium on the campus of the College of Southern Nevada in Henderson. But they would forgo their inaugural season as Lied Field will not be ready in time for the start of the season. The franchise folded in 2012 after failing to attract attention and secure new ownership. They would've been the second professional franchise to play in the Las Vegas area. The first is the Las Vegas 51s of the Triple-A Pacific Coast League.

The team originally began in 2007 as the St. George RoadRunners of the now-defunct Golden Baseball League, replacing the suspended San Diego Surf Dawgs for the 2007 season. They played their home games for their entire run in Utah at Bruce Hurst Field at Dixie State College in St. George. Former major league right fielder Cory Snyder was named the team's first manager that same year and remained there until 2010. Jerry Turner served as bench coach.

On July 5, 2009, the RoadRunners clinched its first playoff spot in team history by winning the GBL Southern Division 1st Half title after defeating the defending GBL champion Orange County Flyers, 4–2, in Fullerton, California. They hosted the 2009 GBL All-Star Game on July 14 at Bruce Hurst Field.

On December 9, 2009, it was announced that the RoadRunners would fold after three seasons, citing poor attendance as its main factor. Ironically, their now-former owners XnE, Inc., were granted a new expansion franchise, the Maui-based Na Koa Ikaika Maui, just months earlier. Snyder left the RoadRunners to become the new manager in Maui.

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