Song's main focus was on leisure traffic between the northeastern United States and Florida, a market where it competed with JetBlue Airways. It also operated flights between Florida and the West Coast, and from the Northeast to the west coast.

Song's aircraft were fitted with leather seats and free personal entertainment systems at every seat, with audio MP3 programmable selections, trivia games that could be played against other passengers, a flight tracker, and satellite television (provided by the DISH Network). Song offered free beverages, but charged for meals and liquor. Both brand-name snack boxes and healthy organic meals were offered. The flight safety instructions were sung or otherwise artistically interpreted, depending on the cabin crew. In addition to crew uniforms designed by Kate Spade, customized cocktails created by nightlife impresario Rande Gerber and an in-flight exercise program designed by New York City fitness guru David Barton, the airline created its own distinct mark in the industry. The Song brand was placed on more than 200 flights a day which carried over ten million passengers.

Song's last flight took off on April 30, 2006. Service shifted to mainline Delta on May 1, 2006.

On January 1, 2008, Delta began repainting the last aircraft bearing the Song livery into mainline Delta Air Lines colors.

Before Song began service on April 15, 2003 as a low-cost Delta brand, the service engaged in a long-term branding strategy that identified a particular strata of hip, style-conscious professional women as their target market. Song's goal was to meet not only their consumers' travel needs but social needs also. Portions of this branding process are documented in the 2004 Frontline episode "The Persuaders" and in the episode's additional materials. The name, brand identity, cabin interiors and airport environments were designed by Landor Associates in New York.

It was promoted by The Apprentice television show, and they had a boutique called "song in the city" to showcase the product in the SoHo district of New York.Boston's Prudential Center also hosted a storefront location.

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