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Sodium-proton antiporter

Na+/H+ antiporter 1
1zcd opm.png
Identifiers
Symbol Na_H_antiport_1
Pfam PF06965
InterPro IPR004670
TCDB 2.A.36
OPM superfamily 346
OPM protein 1zcd

Sodium/proton antiporters are essential secondary-active transporters for sodium and pH homeostasis. Defects in sodium/proton antiporters may result in heart or kidney failure.

There are several families of sodium/proton antiporters that facilitate the exchange of sodium ions with protons across the lipid membrane. Some of them include:

This article incorporates text from the public domain Pfam and InterPro IPR004670


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