Na+/H+ antiporter 1 | |||||||||
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Identifiers | |||||||||
Symbol | Na_H_antiport_1 | ||||||||
Pfam | PF06965 | ||||||||
InterPro | IPR004670 | ||||||||
TCDB | 2.A.36 | ||||||||
OPM superfamily | 346 | ||||||||
OPM protein | 1zcd | ||||||||
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Available protein structures: | |
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Pfam | structures |
PDB | RCSB PDB; PDBe; PDBj |
PDBsum | structure summary |
Sodium/proton antiporters are essential secondary-active transporters for sodium and pH homeostasis. Defects in sodium/proton antiporters may result in heart or kidney failure.
There are several families of sodium/proton antiporters that facilitate the exchange of sodium ions with protons across the lipid membrane. Some of them include:
This article incorporates text from the public domain Pfam and InterPro IPR004670