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Short-gut syndrome

Short bowel syndrome
Synonyms Short gut syndrome, short gut, intestinal failure
ResectedIleum.jpg
A piece of diseased ileum following removal by surgery.
Specialty Gastroenterology
Symptoms Diarrhea, dehydration, malnutrition, weight loss
Complications Anemia, kidney stones
Causes Surgical removal of a large portion of the small intestine
Risk factors Crohn's disease, necrotising enterocolitis
Treatment Specific diet, medications, surgery
Medication Antibiotics, antacids, loperamide, teduglutide, growth hormone
Prognosis Depends on amount of small bowel remaining
Frequency 3 per million per year
Classification
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External resources

Short bowel syndrome (SBS, or simply short gut) is a malabsorption disorder caused by a lack of functional small intestine. The primary symptom is diarrhea, which can result in dehydration, malnutrition, and weight loss. Other symptoms may include bloating, heartburn, feeling tired, lactose intolerance, and foul smelling stool. Complications can include anemia and kidney stones.

Most cases are due to the surgical removal of a large portion of the small intestine. This is most often required due to Crohn's disease in adults and necrotising enterocolitis in young children. Other causes include damage to the small intestine from other means and being born with an abnormally short intestine. It usually does not develop until less than 2 m (6.6 ft) of the normally 6.1 m (20 ft) small intestine remains.

Treatment may include a specific diet, medications, or surgery. The diet may include slightly salty and slightly sweet liquids, vitamin and mineral supplements, small frequent meals, and the avoidance of high fat food. Occasionally nutrients need to be given through an intravenous line, known as parenteral nutrition. Medications used may include antibiotics, antacids, loperamide, teduglutide, and growth hormone. Different types of surgery, including an intestinal transplant, may help some people.


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