The Cross with large enamels, or Senkschmelz Cross, known in German as the Senkschmelzen-Kreuz or the Kreuz mit den großen Senkschmelzen (Cross with large senkschmelz enamels) is a processional cross in the Essen Cathedral Treasury which was created under Mathilde, Abbess of Essen. The name refers to its principal decorations, five unusually large enamel plaques made using the senkschmelz technique, a form of cloisonné which looks forward to champlevé enamel, with a recessed area in enamel surrounded by a plain gold background, and distinguishes it from three other crosses of the crux gemmata type at Essen. The cross is considered one of the masterpieces of Ottonian goldsmithing.
The original part of the cross is 46 cm high and 33 cm wide, with a core made of oak excluding the later fitting at the base. It is a Latin cross with block-shaped ends. These appear similar to the cubic capitals which were popular in architecture around the year 1000. The front of the cross is covered with a highly decorated gold sheet, the back, with one of gilded copper, later in date, which is engraved and partly decorated in relief. The cross is a pure crux gemmata, in which the senkshmelz plaque at the centre shows the Crucifixion of Jesus. The Cross with large enamels is closely related to three other processional crosses in Essen, two of which, the Cross of Otto and Mathilde and the Cross of Mathilde were also donated by Abbess Mathilde. Just like the oldest of these, the Cross of Otto and Mathilde, it has an internal cross, surrounded by a border. While the border of the older cross is composed of gemstones each accompanied by two pearls, the border of the Cross with large enamels also included 24 small enamels (of which 21 still survive), which alternate with gemstones each accompanied by four pearls. The area of the Cross with large enamels inside the border is decorated with skilfully doubled filigree, gemstones, pearls arranged in the shape of crosses and an ancient cameo. On the cameo is a head of Medusa, technically referred to as a Gorgoneion. It is sardonyx and was made in the first half of the first century AD. The cameo is worked in three layers (grey-brown, white, and gold-brown) and has a maximum diameter of 2.7 cm. The cameo might be taken in reference to Psalm 91.13 as symbolic of evil's defeat by the saviour.