Scott A. Strobel | |
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Nationality | American |
Alma mater | Brigham Young University, California Institute of Technology, University of Colorado, Boulder |
Known for | Rainforest Expedition Lab |
Scientific career | |
Fields | Biochemistry |
Institutions | Yale University |
Doctoral advisor | Peter Dervan |
Other academic advisors | Thomas Cech |
Scott A. Strobel is the Henry Ford II Professor of Molecular Biophysics and Biochemistry at Yale University and the vice-president of West Campus Planning and Program Development. He has been a Professor with the Howard Hughes Medical Institute (HHMI) since 2006. He earned a B.A. in Biochemistry from Brigham Young University and a Ph.D. in Biology from the California Institute of Technology, under the guidance of Peter Dervan, before doing postdoctoral research at the University of Colorado, Boulder, under the mentorship of Thomas Cech.
Strobel's lab focuses on the biophysics and biochemistry of catalytic RNAs including riboswitches and the peptidyl transferase center. His group developed the early methods of Nucleotide Analog Interference Mapping used to determine the importance of particular functional groups in a structured RNA molecule. Strobel's group solved the x-ray crystal structure of the full length Azoarcus Group I catalytic intron (PDB entries 1U6B, 1ZZN, 3BO2), the glmS ribozyme (e.g., PDB 3G9C), and the c-di-GMP riboswitch (e.g., PDB 3IRW, 3Q3Z). He has also collaborated with the Steitz lab at Yale on structural studies toward better understanding the mechanism of ribosomal peptide synthesis.