Sandalore

Sandalore

Names
Preferred IUPAC name 3-Methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pentan-2-ol
Other names Sandal pentanol
Identifiers
CAS Number	65113-99-7
3D model (Jmol)	Interactive image
ChemSpider	93216
ECHA InfoCard	100.059.485
InChI InChI=1S/C14H26O/c1-10(12(3)15)6-8-13-9-7-11(2)14(13,4)5/h7,10,12-13,15H,6,8-9H2,1-5H3 Key: NGYMOTOXXHCHOC-UHFFFAOYSA-N
SMILES CC1=CCC(C1(C)C)CCC(C)C(C)O
Properties
Chemical formula	C14H26O
Molar mass	210.36 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Sandalore is a synthetic sandalwood odorant with odor in some ways similar to sandalwood and consequently used in perfumes, emollients, and skin cleaning agents. Sandalore, and the similar brahmanol, have been identified as agonists of the cutaneous olfactory receptor OR2AT4, and found to induce strong Ca²⁺ signals in cultured human keratinocytes. The long-term stimulation of keratinocytes with Sandalore positively affected cell proliferation and migration, and regeneration of keratinocyte monolayers in an in vitro wound scratch assay (i.e., sandalore stimulation also enhanced epidermal "wound healing" in human skin organ cultures). Natural sandalwood oil and other synthetic sandalwood odorants did not have the same effect.