Sambre-et-Meuse was a department of the First French Empire in present-day Belgium. It was named after the rivers Sambre and Meuse. Its capital was Namur.
The department came into existence in 1795, when the Southern Netherlands were occupied by the French. It was formed from most of the county of Namur and parts of the bishopric of Liège and the duchies of Brabant and Luxembourg.
After Napoleon was defeated in 1814, the department became part of the United Kingdom of the Netherlands. Its territory is now divided between the Belgian provinces of Namur and Luxembourg (a small part).
The department was subdivided into the following arrondissements and cantons (situation in 1812):
Coordinates: 50°28′N 4°52′E / 50.467°N 4.867°E