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Salicylanilide

Salicylanilide
Salicylanilide.svg
Names
IUPAC name
2-Hydroxy-N-phenylbenzamide
Other names
2-Hydroxybenzanilide
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.001.571
PubChem CID
UNII
Properties
C13H11NO2
Molar mass 213.24 g·mol−1
Appearance White to off-white crystalline solid
Melting point 136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
Xi
R-phrases R36/37/38
S-phrases S36/37/39
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as disinfectants with antibacterial and antifungal activities.

Bromochlorosalicylanilide

Niclosamide

Oxyclozanide

Rafoxanide

Salicylanilides may be used as antiseptics.


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