Salampsio was the eldest daughter of Herod the Great by his royal Hasmonean wife, Mariamne I. She was married to Phasael ben Phasael, Herod's nephew (her first cousin). The marriage resulted in five children: Antipater, Herod, Alexander, Alexandra, and Cypros. Cypros married Agrippa I, the son of Aristobulus; and Alexandra married Timius of Cyprus.