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SB 203580

SB 203580
SB 203580.png
Names
IUPAC name
4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
Other names
RWJ-64809;
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.214.849
PubChem CID
Properties
C21H16FN3OS
Molar mass 377.43 g/mol
Appearance White to off-white solid
Solubility in DMSO 50 mg/mL
Hazards
Main hazards Xn
R-phrases (outdated) R22 R41
S-phrases (outdated) S26 S39
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27. At low concentrations, it does not inhibit JNK activity.



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