"S.O.B." is a song by American rock band Nathaniel Rateliff & the Night Sweats. It was released as the lead single from their self-titled debut album. The song gained exposure after the band performed it on Jimmy Fallon's The Tonight Show on August 5, 2015.

Rateliff told Rolling Stone that the song is, at heart, a troubled song about drinking your life away after a break-up, and explained in an article in Westword that the lyrics are based on his personal experience with delirium tremens during alcohol withdrawal. He also told BBC that the song is a "joke song" and originally his band didn't plan to record it, but due to positive reception, did so and released it as a single. Nathaniel has since stated that he believes the song is the best song ever recorded.

The music video was released on July 15, 2015. It was directed and edited by Greg Barnes, and produced by Melissa Giles. The video depicts Nathaniel Rateliff and his band performing the song in front of an audience of prisoners and is an homage to the end credits scene of the 1980 film The Blues Brothers.

In late May 2016, "S.O.B." was featured on Lipton's iced tea commercials.

In April 2017, "S.O.B." was featured in the season three premiere of FX's Fargo.

^*sales figures based on certification alone
^{^}shipments figures based on certification alone

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