Rose Walker is a fictional character from the Sandman series written by Neil Gaiman. She makes her first appearance in issue #10, part one of The Doll's House story arc. She is a beautiful young girl, a blonde with red- and purple-dyed streaks in her hair. (In later issues she is shown as having red hair with a blonde streak.) There are various indications that Rose is, or became, one of the immortals occasionally featured in Sandman. Desire of the Endless is Rose's maternal grandparent (so identified, because androgynous), and Rose, therefore, is often desired by others.
When she first appears, Rose is awakened by her mother, Miranda, from a dream. Upon attempting to recount the dream to her mother, Rose is ignored; a caption of her internal reveals her mother "wasn't interested in dreams, back then". She and her mother are traveling to England to see a woman named Unity Kinkaid. On the way, Rose has another dream in which she sees Morpheus and Lucien, talking about a "dream vortex" (Rose herself), which might destroy Morpheus' realm. In England, Rose and her mother learn that Unity Kinkaid is actually Miranda's mother and Rose's grandmother: a victim of the 'sleepy sickness' that resulted from Morpheus' capture, during which she was impregnated and caused to give birth in her sleep. Because Rose's brother Jed is missing, Rose goes in search of him; eventually to Florida, where she finds a place to stay in a large boarding-house near Cape Canaveral. With the help of her neighbor Gilbert and Morpheus, Rose saves Jed from a convention of serial killers; but is herself sentenced to death by Morpheus, to prevent her vortex from destroying the Dreaming. Unity, on grounds that the vortex originally belonged to her, exchanges her own life for Rose's, and dies; whereupon Morpheus learns that his sibling Desire had conceived Rose's mother on sleeping Unity, to trick Morpheus into killing Rose.