The Catholic Church in Azerbaijan is part of the worldwide Catholic Church, under the spiritual leadership of the Pope in Rome. There are about 570 local Roman Catholics in the country as of 2016. Azerbaijan is covered entirely by a single Apostolic Prefecture since 2011. The community is served by seven Salesian priests and two friars. In addition, there is a mission of the Missionaries of Charity.
Christians have been present in Azerbaijan since the 1st century AD. Starting from 1320, Catholic missionaries such as Jordanus and Odoric of Pordenone have visited what is now Azerbaijan and have established missions mostly in large cities. In the 14th century in Nakhchivan alone, there were 12 missions led by Dominicans, Capuchins, Augustinians, etc. In 1660 Superior of the Capuchin Mission at Isfahan, friar reported Catholic parishes functioning in Baku and Shamakhi. Jesuits arrived and set a mission in Ganja in the 1680s.
In the 14th and 15th centuries, efforts of Bartholomew, a Dominican missionary from Bologna, resulted in the conversion of 28 settlements in Nakhchivan into Roman Catholicism. Despite hardships and pressure from the Armenian Apostolic Church, Catholicism survived here for over three centuries, after which it went into decline and by the 1800s was no longer practiced.
With the establishment of the Russian rule, these lands became a popular destination for members of various Christian denominations. Catholics were represented by ethnic Poles who started immigrating to Baku and Shemakhi in the mid-19th century, Ukrainians, Georgian Catholics, Armenian Catholics, as well as Western Europeans who stayed in Baku on a temporary or permanent basis.