"Roc Boys (And the Winner Is)..." is the second single from Jay-Z's tenth studio album, American Gangster. The song is produced by Diddy and two of his producers known as LV and Sean C from his production team, The Hitmen. It features additional vocals by Beyoncé, Kanye West and Cassie. The song samples "Make the Road by Walking" by The Menahan Street Band. On December 11, 2007, Rolling Stone named it the best song of 2007.

The music video was directed by Chris Robinson and costume designed by June Ambrose. The video was shot in New York City in Jay-Z's The 40/40 Club.

The intro of the video contains the chorus from Hello Brooklyn 2.0. The video features cameo appearances by Nas, Rick Ross, Memphis Bleek, Diddy, Freeway, Terrence J, Tru Life, Young Gunz, Jadakiss, Yaya DaCosta, Swizz Beatz, Drew Sidora, Kristia Krueger, Chain 4, Chantel, Beanie Sigel, Cassie, DJ Clue, Larry Johnson, Tristan Wilds, Just Blaze, Zab Judah, The-Dream, Irv Gotti and Mariah Carey. Kanye West is not featured in the video because of a scheduling conflict, at the time he was on tour in Dubai, as posted in his blog.