Ritalinic acid

Ritalinic acid

Clinical data
ATC code	None
Legal status
Legal status	US: Unscheduled
Identifiers
IUPAC name Phenyl(piperidin-2-yl)acetic acid
CAS Number	19395-41-6 Y
PubChem CID	86863
ChemSpider	78360 Y
ECHA InfoCard	100.039.094
Chemical and physical data
Formula	C13H17NO2
Molar mass	219.28 g/mol
3D model (JSmol)	Interactive image
SMILES C1CCNC(C1)C(C2=CC=CC=C2)C(=O)O
InChI InChI=InChI=1S/C13H17NO2/c15-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-14-11/h1-3,6-7,11-12,14H,4-5,8-9H2,(H,15,16) Y Key:INGSNVSERUZOAK-UHFFFAOYSA-N Y

Ritalinic acid is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate and ethylphenidate. When administered orally, methylphenidate is extensively metabolized in the liver by hydrolysis of the ester group yielding ritalinic acid. The hydrolysis was found to be catalyzed by carboxylesterase 1 (CES1).