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Richard Lewisohn

Richard Lewisohn
Born (1875-06-12)June 12, 1875
Hamburg, Germany
Died August 11, 1961(1961-08-11) (aged 86)
New York City
Fields Surgery
Institutions Mount Sinai Hospital (Manhattan)
Alma mater University of Freiburg
Known for Use of sodium citrate to prevent clotting in blood

Richard Lewisohn (July 12, 1875 in Hamburg – August 11, 1961 in New York) was a German-American surgeon. At Mount Sinai Hospital in Manhattan, he developed procedures that made blood transfusion practical.

Lewisohn was educated at the local Gymnasium from where he entered medical school in Kiel in 1893. As was typical for German medical students, he attended several different medical schools, before receiving his doctorate from the University of Freiburg in 1899 with a thesis on malignant kidney tumors. He then served for two years as an assistant to Karl Weigert at the Senckenberg Institute in Frankfurt. In 1904 he became an assistant to Geheimrat Czerny in Heidelberg. In 1906 he emigrated to New York, where he became a gastroenterologist and surgeon; from 1928 to 1936 he was chief of the general surgical service at Mount Sinai.

Following early speculation and its use in animal transfusion, in April 1914 Belgian physician Albert Hustin used sodium citrate to prevent donated blood from clotting during transfusion.Luis Agote had also used a citrate method at Buenos Aires on 14 November 1914. Working independently, Lewisohn's contribution, in 1915, was to determine the optimal concentration of sodium citrate for preserving blood products without inducing toxicity (0.2% for transfusions not exceeding 5g). Correct use of sodium citrate made it possible to preserve blood products for longer and longer periods of time allowing donor and donee to be geographically separate. His research was put into use during the First World War though it was only introduced to British medical services in 1917 (by Oswald Robertson).

In 1922, he convinced his colleague Albert Berg to perform the first subtotal gastrectomy for peptic ulcer in the United States. He had traveled previously to Hans von Haberer in Innsbruck, Austria, where the method had already been applied and where he became familiar with the surgical techniques. Following the successful application at Mount Sinai, the technique spread to the rest of the United States for ulcers resistant to other treatment. Lewisohn was also a contemporary of Alexis Moschcowitz and his successor as chief of the general surgical service at Mount Sinai.


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