The Rheinsberg Lake Region (German: Rheinsberger Seengebiet) with its many great and small lakes, lies in the richly-varied, gently rolling, forested countryside between the villages of Rheinsberg, Menz and Fürstenberg/Havel in the north German state of Mecklenburg-Vorpommern. It lies just to the south of the Neustrelitz Little Lakes Region, but has no natural link to the waterbodies to the north. However, the Rheinsberg Lake Region is linked to the Neustrelitz lakes via the Wolfsbruch Canal and Lock, the Müritz-Havel Waterway and the Upper Havel Waterway. It drains southwards to the River Havel through the Rhin and is bounded by Ruppin Switzerland to the south. The overwhelming part of the region belongs to the Stechlin-Ruppiner Land Nature Park. The Stechlin Nature Reserve, created in 1938, is well known.
The best-known lake in the Rheinsberg Lake Region is Lake Stechlin (Stechlinsee). Other large lakes in the region are the: Braminsee, Nehmitzsee, Großer Prebelowsee, Rheinsberger See, Roofensee, Schwarzer See, Tietzowsee, Großer Wummsee, Großer Zechliner See and Zootzensee.
In 1876-1881 the chains of lakes within the Rheinsberg Lake Region known as the Rheinsberg and Zechlin Waters (Rheinsberger Gewässer and Zechliner Gewässer), stretching for about 21 kilometres (13 mi), were made navigable and connected to the Müritz-Havel Waterway via the Wolfsbruch Lock.