The architecture of the Portuguese Renaissance intimately linked to Gothic architecture and gradual in its classical elements. The Manueline style (circa 1490-1535) was a transitional style that combined Renaissance and Gothic ornamental elements to buildings that were architectonically closer to Gothic architecture, as is the Isabelline style of Spain. Manueline was succeeded by a brief Early Renaissance phase (c. 1530-1550), closer to Classical canons, followed by the adoption of Mannerist (late Renaissance) forms. Portuguese Mannerism, specially in secular architecture, is characterised by simplicity in the organisation of façades and relative lack of decoration, being often referred to as Estilo Chão (plain style). Even with the arrival of Baroque architecture in the late 17th century, Portuguese architecture continued to use Mannerist forms well into the 18th century.
One of the most important examples of Manueline style is the Jerónimos Monastery at Lisbon, in which Renaissance ornaments decorate portals, church columns and closters. The definitive abandonment of Gothic architecture and the first "pure" Renaissance structures appear later in the 16th century, under King John III, like the Chapel of Nossa Senhora da Conceição in Tomar (1532–40), the Porta Especiosa of Coimbra Cathedral and the Graça Church at Évora (c. 1530-1540), as well as the cloisters of the Cathedral of Viseu (c. 1528-1534) and Convent of Christ in Tomar (John III Cloisters, 1557–1591).
Manueline churches like that of Jerónimos Monastery anticipated the unification of inner space (see Hall Church) that would characterise Renaissance churches like the Mercy Church of Santarém (after 1559), the Santo Antão Church of Évora (1557–63) and the cathedrals of Leiria (after 1550) and Portalegre (after 1556).