Reinoud I van Brederode (English: Raynald) (Santpoort, 1336–1390) was the 6th lord of Brederode.
He was a son of Dirk III van Brederode and Beatrix van Heinsberg van Valkenberg. In 1358 Reinoud was appointed bailiff of Kennemerland by Albert I, count of Holland. In the same year an assassination attempt was made on him at Castricumerzand. On 11 November 1377 he succeeded his father as lord of Brederode. Reinoud supported Machteld of Guelders in her struggle for the county of Guelders from 1371 to 1379.
Reinoud married in 1366 with Jolanda van Gennep van der Eem, a daughter of Jan II van Gennep. They had at least four children: