Rancho Mallacomes (also called Moristul and Mallacomes y Plano de Agua Caliente) was a 17,742-acre (71.80 km2) Mexican land grant in present day Napa County and Sonoma County, California given in 1843 by Governor Manuel Micheltorena to José de los Santos Berreyesa.
The grant was located in the Napa Valley, just north of present day Calistoga and consisted of Mallacomes or Moristul and Plano de Agua Caliente. Mallacomes comes from mountain chain Serro de los Mallacomes (Mount Saint Helena) and included most of Knights Valley (previously known as Mallacomes Valley). Agua Caliente refers to the warms springs near Calistoga.
José Santos Berreyesa (1817 – 1864) was the son of José de los Reyes Berreyesa (1785 - 1846), the grantee of Rancho San Vicente. José Santos Berreyesa was a soldier at the Presidio of Sonoma from 1840 - 1842, and alcalde in 1846. He was jailed with two of his brothers by John C. Frémont in 1846 during the Bear Flag Revolt.
With the cession of California to the United States following the Mexican-American War, the 1848 Treaty of Guadalupe Hidalgo provided that the land grants would be honored. As required by the Land Act of 1851, a claim for Rancho Mallacomes was filed by José de los Santos Berreyesa with the Public Land Commission in 1852, and 12,540 acres (50.7 km2) patented in 1873.