R-ICE chemotherapy

ICE in the context of chemotherapy is an acronym for one of the chemotherapy regimens, used in salvage treatment of relapsed or refractory non-Hodgkin's lymphoma and Hodgkin lymphoma.

In case of CD20-positive B cell lymphoid malignancies the ICE regimen is often combined today with rituximab. This regimen is then called ICE-R or R-ICE or RICE.

[R]-ICE regimen consists of:

Cycles are repeated every 14 days for 3 cycles, then high-dose chemotherapy with autologous stem cell transplant follows (if the patient is considered eligible for HDCT and ASCT).

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