Quartzburg (earlier, Burns' Creek, Burns' Camp, Burns' Ranch, and Burns' Diggings) is a former settlement in Mariposa County, California. It was located on Burns Creek 2 miles (3.2 km) upstream from Hornitos.
John and Robert Burns settled at the site in 1847. A mining camp grew up. A post office operated at Quartzburg from 1851 to 1861. The name "Quartzburg" was bestowed by Thomas Thorn due to the quartz outcroppings at the place.