Pyrin domain
| PAAD/DAPIN/Pyrin domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 |
|||||||||
| Identifiers | |||||||||
| Symbol | PAAD_DAPIN | ||||||||
| Pfam | PF02758 | ||||||||
| Pfam clan | CL0041 | ||||||||
| InterPro | IPR004020 | ||||||||
| PROSITE | PS50824 | ||||||||
| SCOP | 1pn5 | ||||||||
| SUPERFAMILY | 1pn5 | ||||||||
| CDD | cd08305 | ||||||||
|
|||||||||
| Available protein structures: | |
|---|---|
| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
A pyrin domain is a protein domain and a subclass of protein motif known as the death fold; it allows a pyrin domain containing protein to interact with other proteins that contain a pyrin domain. It is also known as a PYD or PAAD/DAPIN domain, and is distantly evolutionarily related to the Death domain family of protein domains. Proteins containing a pyrin domain are frequently involved in biological processes called inflammation and apoptosis. Proteins that possess a pyrin domain include intracellular microbial sensors called NOD-like receptors, and proteins associated with their function, such as PYCARD and certain fish caspases.
...
Wikipedia